Research workbench
Crystal structure of the IMP4-MPP10 complex from chaetomium thermophilum
Analyse Crystal structure of the IMP4-MPP10 complex from chaetomium thermophilum in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5O9E
- Type
- protein
- Length
- 281 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative U3 small nucleolar ribonucleoprotein; Putative U3 small nucleolar…
- UniProt
- G0SE90, G0S9I7
- Pockets
- 3 · best druggability 0.50
Structure
x-ray diffraction · 2 distinct chains · 30% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative U3 small nucleolar ribonucleoprotein | protein | 201 | 20% helix, 39% strand | G0SE90 |
| B | Putative U3 small nucleolar ribonucleoprotein protein | protein | 80 | 56% helix, 4% strand | G0S9I7 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 88 | 0.50 | 0.83 | 24 | EDO |
| 2 | 89 | 0.49 | 0.82 | 20 | empty |
| 3 | 104 | 0.41 | 0.77 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 2155 Ų buried · 30 hydrogen bonds · protein-protein
Compared structures
- 5O9E · Crystal structure of the Imp4-Mpp10 complex from Chaetomium thermophilum · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G0SE90
- Every structure of UniProt G0S9I7
- Elsewhere: RCSB PDB 5O9E · PDBe 5O9E · UniProt G0SE90 · UniProt G0S9I7
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