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Crystal structure of a taiwan habu venom metalloproteinase complexed with pekw.

Analyse Crystal structure of a taiwan habu venom metalloproteinase complexed with pekw. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1KUK
Type: protein
Length: 204 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Metalloproteinase; Ekw
EC: 3.4.24.44
UniProt: O57413
Ligands: CD

Structure

x-ray diffraction · 2 distinct chains · 40% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Metalloproteinase (EC 3.4.24.44)	protein	201	40% helix, 17% strand	O57413
B	Ekw	protein	3	0% helix, 33% strand	—

Ligands and binding sites

CD · Cadmium ion · metal · 10 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 420 Å² buried · 11 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 disulfide, 1 modified (disulfide, cyclization).

Compared structures

1KUK · Crystal Structure of a Taiwan Habu Venom Metalloproteinase complexed with pEKW. · the same entry in another collection · chain A against A, TM-score 1.00
O57413 · AlphaFold monomer V2.0 prediction for zinc METALLOPROTEINASE/DISINTEGRIN (O57413) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O57413
Elsewhere: RCSB PDB 1KUK · PDBe 1KUK · UniProt O57413

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