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Structural genomics, protein EC1535

Analyse Structural genomics, protein EC1535 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1KTN
Type: protein
Length: 499 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 2-deoxyribose-5-phosphate aldolase
EC: 4.1.2.4
UniProt: P0A6L0
Pockets: 4 · best druggability 0.65

Structure

x-ray diffraction · 2 distinct chains · 49% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	2-deoxyribose-5-phosphate aldolase (EC 4.1.2.4)	protein	250	49% helix, 16% strand	P0A6L0
B	2-deoxyribose-5-phosphate aldolase (EC 4.1.2.4)	protein	249	49% helix, 16% strand	P0A6L0

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	221	0.65	0.83	29	empty
2	230	0.62	0.82	31	empty
3	117	0.51	0.81	21	empty
4	110	0.48	0.80	23	empty

Interfaces

1 interface between chains.

A–B · 639 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

1KTN · Structural Genomics, Protein EC1535 · the same entry in another collection · chain A against A, TM-score 1.00
P0A6L0 · AlphaFold monomer V2.0 prediction for deoxyribose-phosphate aldolase (P0A6L0) · a predicted model of the same protein · chain B against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A6L0
Elsewhere: RCSB PDB 1KTN · PDBe 1KTN · UniProt P0A6L0

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