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Neutral trehalase NTH1 from saccharomyces cerevisiae

Analyse Neutral trehalase NTH1 from saccharomyces cerevisiae in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5NIS
Type: protein
Length: 550 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Neutral trehalase
EC: 3.2.1.28
UniProt: P32356
Pockets: 8 · best druggability 0.63

Structure

x-ray diffraction · 1 distinct chain · 52% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Neutral trehalase (EC 3.2.1.28)	protein	550	52% helix, 9% strand	P32356

Pockets

8 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	331	0.63	0.79	27	empty
2	179	0.49	0.77	23	empty
3	131	0.46	0.77	24	empty
4	126	0.39	0.74	18	empty
5	101	0.37	0.75	27	empty

Compared structures

5NIS · Neutral trehalase Nth1 from Saccharomyces cerevisiae · the same entry in another collection · chain A against A, TM-score 1.00
P32356 · AlphaFold monomer V2.0 prediction for neutral trehalase (P32356) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P32356
Elsewhere: RCSB PDB 5NIS · PDBe 5NIS · UniProt P32356

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