Research workbench
Solution structure of detergent-solubilized RCF1, a yeast mitochondrial inner membrane protein involved in respiratory complex III/IV supercomplex formation
Analyse Solution structure of detergent-solubilized RCF1, a yeast mitochondrial inner… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5NF8
- Type
- protein
- Length
- 318 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Respiratory supercomplex factor 1, mitochondrial
- UniProt
- B3LLM2
- Pockets
- 6 · best druggability 0.84
Structure
solution nmr · 1 distinct chain · 71% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Respiratory supercomplex factor 1, mitochondrial | protein | 159 | 71% helix, 0% strand | B3LLM2 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 824 | 0.84 | 0.86 | 80 | empty |
| 2 | 104 | 0.59 | 0.86 | 21 | empty |
| 3 | 73 | 0.47 | 0.82 | 19 | empty |
| 4 | 85 | 0.43 | 0.79 | 15 | empty |
| 5 | 73 | 0.35 | 0.77 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 1209 Ų buried · 24 hydrogen bonds · protein-protein
Compared structures
- 5NF8 · Solution structure of detergent-solubilized Rcf1, a yeast mitochondrial inner membrane… · the same entry in another collection · chain A against A, TM-score 1.00
- B3LLM2 · AlphaFold monomer V2.0 prediction for respiratory supercomplex factor 1, mitochondrial… · a predicted model of the same protein · chain A against A, TM-score 0.31
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B3LLM2
- Elsewhere: RCSB PDB 5NF8 · PDBe 5NF8 · UniProt B3LLM2
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