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Ketopantoate reductase from escherichia COLI

Analyse Ketopantoate reductase from escherichia COLI in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1KS9
Type: protein
Length: 291 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 2-dehydropantoate 2-reductase
EC: 1.1.1.169
UniProt: P0A9J4
Pockets: 2 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 47% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	2-dehydropantoate 2-reductase (EC 1.1.1.169)	protein	291	47% helix, 20% strand	P0A9J4

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	594	0.66	0.77	52	empty
2	55	0.32	0.76	13	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

1KS9 · Ketopantoate Reductase from Escherichia coli · the same entry in another collection · chain A against A, TM-score 1.00
P0A9J4 · AlphaFold monomer V2.0 prediction for 2-dehydropantoate 2-reductase (P0A9J4) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A9J4
Elsewhere: RCSB PDB 1KS9 · PDBe 1KS9 · UniProt P0A9J4

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