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Influenza D virus nucleoprotein

Analyse Influenza D virus nucleoprotein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5N2U
Type: protein
Length: 1,872 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nucleoprotein
UniProt: A0A0E3VZU8
Pockets: 20 · best druggability 0.86

Structure

x-ray diffraction · 4 distinct chains · 46% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nucleoprotein	protein	469	42% helix, 11% strand	A0A0E3VZU8
B	Nucleoprotein	protein	460	47% helix, 9% strand	A0A0E3VZU8
C	Nucleoprotein	protein	467	46% helix, 11% strand	A0A0E3VZU8
D	Nucleoprotein	protein	476	47% helix, 10% strand	A0A0E3VZU8

Pockets

20 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1159	0.86	0.87	103	empty
2	300	0.65	0.81	43	empty
3	113	0.62	0.87	20	empty
4	179	0.62	0.84	31	empty
5	127	0.61	0.86	20	empty

Interfaces

4 interfaces between chains.

C–D · 2362 Å² buried · 33 hydrogen bonds · protein-protein
A–D · 2288 Å² buried · 38 hydrogen bonds · protein-protein
B–C · 2273 Å² buried · 41 hydrogen bonds · protein-protein
A–B · 2174 Å² buried · 37 hydrogen bonds · protein-protein

Compared structures

5N2U · Influenza D virus nucleoprotein · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0E3VZU8
Elsewhere: RCSB PDB 5N2U · PDBe 5N2U · UniProt A0A0E3VZU8

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