Research workbench
Crystal structure of UTP4 from chaetomium thermophilum
Analyse Crystal structure of UTP4 from chaetomium thermophilum in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5N1A
- Type
- protein
- Length
- 1,409 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- UTP4
- UniProt
- G0SCT7
- Pockets
- 20 · best druggability 0.86
Structure
x-ray diffraction · 2 distinct chains · 5% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | UTP4 | protein | 703 | 5% helix, 48% strand | G0SCT7 |
| B | UTP4 | protein | 706 | 4% helix, 48% strand | G0SCT7 |
Pockets
20 pockets found on a 1 Å grid, 13 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 923 | 0.86 | 0.88 | 88 | empty |
| 2 | 976 | 0.86 | 0.87 | 87 | empty |
| 3 | 980 | 0.80 | 0.81 | 69 | empty |
| 4 | 860 | 0.80 | 0.82 | 66 | empty |
| 5 | 351 | 0.66 | 0.80 | 48 | empty |
Interfaces
1 interface between chains.
- A–B · 1434 Ų buried · 15 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 30 modified (engineered).
Compared structures
- 5N1A · Crystal structure of Utp4 from Chaetomium thermophilum · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G0SCT7
- Elsewhere: RCSB PDB 5N1A · PDBe 5N1A · UniProt G0SCT7
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