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Solution structure of winged helix protein hfh-1

Analyse Solution structure of winged helix protein hfh-1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1KQ8
Type: protein
Length: 75 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hepatocyte nuclear factor 3 forkhead homolog 1
UniProt: Q63244
Pockets: 1 · best druggability 0.34

Structure

solution nmr · 1 distinct chain · 44% helix, 7% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hepatocyte nuclear factor 3 forkhead homolog 1	protein	75	44% helix, 7% strand	Q63244

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	70	0.34	0.76	14	empty

Compared structures

1KQ8 · Solution Structure of Winged Helix Protein HFH-1 · the same entry in another collection · chain A against A, TM-score 1.00
Q63244 · AlphaFold monomer V2.0 prediction for forkhead box protein Q1 (Q63244) · a predicted model of the same protein · chain A against A, TM-score 0.60

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q63244
Elsewhere: RCSB PDB 1KQ8 · PDBe 1KQ8 · UniProt Q63244

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