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Twitchin kinase fragment (C.ELEGANS), autoregulated protein kinase and immunoglobulin domains

Analyse Twitchin kinase fragment (C.ELEGANS), autoregulated protein kinase and… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1KOA
Type
protein
Length
447 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Twitchin
UniProt
Q23551
Pockets
3 · best druggability 0.59

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 25% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATwitchinprotein44732% helix, 25% strandQ23551

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12070.590.8127empty
21540.490.7817empty
31000.410.7719empty

Compared structures

  • 1KOA · Twitchin kinase fragment (C.ELEGANS), autoregulated protein kinase and immunoglobulin… · the same entry in another collection · chain A against A, TM-score 1.00

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