Research workbench
Hpr KINASE/PHOSPHATASE from mycoplasma pneumoniae
Analyse Hpr KINASE/PHOSPHATASE from mycoplasma pneumoniae in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1KNX
- Type
- protein
- Length
- 1,827 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Probable HPR(SER) KINASE/PHOSPHATASE
- EC
- 2.7.1.-, 3.1.3.-
- UniProt
- P75548
- Pockets
- 20 · best druggability 0.84
Structure
x-ray diffraction · 6 distinct chains · 35% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Probable HPR(SER) KINASE/PHOSPHATASE (EC 2.7.1.-, 3.1.3.-) | protein | 303 | 33% helix, 28% strand | P75548 |
| B | Probable HPR(SER) KINASE/PHOSPHATASE (EC 2.7.1.-, 3.1.3.-) | protein | 304 | 35% helix, 30% strand | P75548 |
| C | Probable HPR(SER) KINASE/PHOSPHATASE (EC 2.7.1.-, 3.1.3.-) | protein | 300 | 36% helix, 30% strand | P75548 |
| D | Probable HPR(SER) KINASE/PHOSPHATASE (EC 2.7.1.-, 3.1.3.-) | protein | 304 | 34% helix, 30% strand | P75548 |
| E | Probable HPR(SER) KINASE/PHOSPHATASE (EC 2.7.1.-, 3.1.3.-) | protein | 310 | 35% helix, 27% strand | P75548 |
| F | Probable HPR(SER) KINASE/PHOSPHATASE (EC 2.7.1.-, 3.1.3.-) | protein | 306 | 35% helix, 28% strand | P75548 |
Pockets
20 pockets found on a 1 Å grid, 14 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1115 | 0.84 | 0.85 | 108 | empty |
| 2 | 1129 | 0.79 | 0.81 | 123 | empty |
| 3 | 884 | 0.76 | 0.80 | 93 | empty |
| 4 | 745 | 0.72 | 0.78 | 68 | empty |
| 5 | 53 | 0.72 | 0.98 | 19 | empty |
Interfaces
12 interfaces between chains.
- E–F · 2411 Ų buried · 28 hydrogen bonds · protein-protein
- C–D · 2366 Ų buried · 34 hydrogen bonds · protein-protein
- A–B · 1943 Ų buried · 16 hydrogen bonds · protein-protein
- D–E · 1358 Ų buried · 15 hydrogen bonds · protein-protein
- C–F · 1350 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P75548
- Elsewhere: RCSB PDB 1KNX · PDBe 1KNX · UniProt P75548
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.