Research workbench
Ceue (H227L variant) a periplasmic protein from campylobacter jejuni
Analyse Ceue (H227L variant) a periplasmic protein from campylobacter jejuni in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5LWQ
- Type
- protein
- Length
- 865 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Enterochelin uptake periplasmic binding protein
- UniProt
- A0A0W8LI20
- Ligands
- NA, BR
- Pockets
- 7 · best druggability 0.72
Structure
x-ray diffraction · 2 distinct chains · 41% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Enterochelin uptake periplasmic binding protein | protein | 289 | 41% helix, 20% strand | A0A0W8LI20 |
| B, C | Enterochelin uptake periplasmic binding protein | protein | 288 | 41% helix, 21% strand | A0A0W8LI20 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 507 | 0.72 | 0.81 | 67 | NA |
| 2 | 722 | 0.68 | 0.76 | 76 | empty |
| 3 | 211 | 0.65 | 0.84 | 39 | empty |
| 4 | 502 | 0.65 | 0.77 | 56 | empty |
| 5 | 236 | 0.64 | 0.82 | 37 | empty |
Interfaces
3 interfaces between chains.
- A–C · 542 Ų buried · 5 hydrogen bonds · protein-protein
- B–C · 413 Ų buried · 1 hydrogen bond · protein-protein
- A–B · 310 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 5LWQ · CeuE (H227L variant) a periplasmic protein from Campylobacter jejuni · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0W8LI20
- Elsewhere: RCSB PDB 5LWQ · PDBe 5LWQ · UniProt A0A0W8LI20
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.