Research workbench
Q136A mutant of toxic shock syndrome toxin-1 from S. aureus
Analyse Q136A mutant of toxic shock syndrome toxin-1 from S. aureus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1AW7
- Type
- protein
- Length
- 776 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Toxic shock syndrome toxin-1
- UniProt
- P06886
- Pockets
- 9 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 16% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Toxic shock syndrome toxin-1 | protein | 194 | 16% helix, 42% strand | P06886 |
Pockets
9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1125 | 0.81 | 0.82 | 115 | empty |
| 2 | 794 | 0.80 | 0.83 | 101 | empty |
| 3 | 353 | 0.63 | 0.79 | 42 | empty |
| 4 | 398 | 0.61 | 0.77 | 30 | empty |
| 5 | 385 | 0.60 | 0.77 | 33 | empty |
Interfaces
4 interfaces between chains.
- C–D · 1236 Ų buried · 24 hydrogen bonds · protein-protein
- A–B · 1223 Ų buried · 23 hydrogen bonds · protein-protein
- B–D · 316 Ų buried · 2 hydrogen bonds · protein-protein
- B–C · 156 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06886
- Elsewhere: RCSB PDB 1AW7 · PDBe 1AW7 · UniProt P06886
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.