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Lambda-[RU(PHEN)2(DPPZ-11,12-ME)]2+ bound to a short substituted DNA sequence

Analyse Lambda-[RU(PHEN)2(DPPZ-11,12-ME)]2+ bound to a short substituted DNA sequence in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
5LFX
Type
DNA
Length
8 nucleotides
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DNA (5'-D(*GP*CP*CP*G)-3'); DNA (5'-D(*(CBR)P*GP*GP*C)-3')
Ligands
9ZQ, BA

Structure

x-ray diffraction · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA (5'-D(*GP*CP*CP*G)-3')dna4——
CDNA (5'-D(*(CBR)P*GP*GP*C)-3')dna4——

Ligands and binding sites

  • 9ZQ · Ru(phen)2(dppz-11,12-Me2) · ligand · chains A, C
  • BA · Barium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–C · 193 Ų buried · 15 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 1 modified (nucleotide modification).

Compared structures

  • 5LFX · Lambda-[Ru(phen)2(dppz-11,12-Me)]2+ bound to a short substituted DNA sequence · the same entry in another collection · chain A against A, TM-score 1.00

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