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Formaldehyde-responsive regulator frmr E64H variant from salmonella enterica serovar typhimurium

Analyse Formaldehyde-responsive regulator frmr E64H variant from salmonella enterica… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5LCY
Type: protein
Length: 354 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Frmr
UniProt: A0A0H3NLH8
Pockets: 1 · best druggability 0.46

Structure

x-ray diffraction · 2 distinct chains · 85% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, D	Frmr	protein	88	85% helix, 0% strand	A0A0H3NLH8
B, C	Frmr	protein	89	84% helix, 0% strand	A0A0H3NLH8

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	187	0.46	0.75	22	empty

Interfaces

6 interfaces between chains.

C–D · 1769 Å² buried · 8 hydrogen bonds · protein-protein
A–B · 1760 Å² buried · 10 hydrogen bonds · protein-protein
B–C · 836 Å² buried · 13 hydrogen bonds · protein-protein
A–D · 760 Å² buried · 15 hydrogen bonds · protein-protein
A–C · 18 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

5LCY · Formaldehyde-Responsive Regulator FrmR E64H variant from Salmonella enterica serovar… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0H3NLH8
Elsewhere: RCSB PDB 5LCY · PDBe 5LCY · UniProt A0A0H3NLH8

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