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Plexin A4 full extracellular region, domains 1 to 10, data to 7.5 ångström, spacegroup P4(1)

Analyse Plexin A4 full extracellular region, domains 1 to 10, data to 7.5 ångström… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5L5K
Type: protein
Length: 1,168 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Plexin-A4
UniProt: Q80UG2
Pockets: 12 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 40% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Plexin-A4	protein	1168	6% helix, 40% strand	Q80UG2

Pockets

12 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	527	0.69	0.79	46	empty
2	109	0.63	0.88	33	empty
3	264	0.60	0.79	31	empty
4	163	0.43	0.74	33	empty
5	59	0.40	0.81	16	empty

Modifications

Observed in the structure: 24 disulfide (disulfide).

Compared structures

5L5K · Plexin A4 full extracellular region, domains 1 to 10, data to 7.5 angstrom, spacegroup… · the same entry in another collection · chain A against A, TM-score 1.00
Q80UG2 · AlphaFold monomer V2.0 prediction for plexin-A4 (Q80UG2) · a predicted model of the same protein · chain A against A, TM-score 0.65

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q80UG2
Elsewhere: RCSB PDB 5L5K · PDBe 5L5K · UniProt Q80UG2

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