Research workbench

RAWV_CTD (helix form) of 16S/23S 2'-O-methyltransferase tlya

Analyse RAWV_CTD (helix form) of 16S/23S 2'-O-methyltransferase tlya in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5KS2
Type: protein
Length: 209 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 16S/23S rRNA (cytidine-2'-O)-methyltransferase tlya
EC: 2.1.1.226, 2.1.1.227
UniProt: P9WJ63
Ligands: CL
Pockets: 2 · best druggability 0.47

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	16S/23S rRNA (cytidine-2'-O)-methyltransferase tlya (EC 2.1.1.226, 2.1.1.227)	protein	209	40% helix, 22% strand	P9WJ63

Ligands and binding sites

CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	140	0.47	0.77	18	CL
2	70	0.37	0.78	16	empty

Compared structures

5KS2 · RAWV_CTD (Helix form) of 16S/23S 2'-O-methyltransferase TlyA · the same entry in another collection · chain A against A, TM-score 1.00
P9WJ63 · AlphaFold monomer V2.0 prediction for 16S/23S rRNA (cytidine-2'-O)-methyltransferase tlya… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P9WJ63
Elsewhere: RCSB PDB 5KS2 · PDBe 5KS2 · UniProt P9WJ63

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