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Structure of NS5 methyltransferase from zika virus bound to S- adenosylmethionine

Analyse Structure of NS5 methyltransferase from zika virus bound to S… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5KQR
Type: protein
Length: 264 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Methyltransferase
UniProt: H9A910
Ligands: SAM, PO4, CL
Pockets: 1 · best druggability 0.63

Structure

x-ray diffraction · 1 distinct chain · 36% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Methyltransferase	protein	264	36% helix, 17% strand	H9A910

Ligands and binding sites

SAM · S-adenosylmethionine · ligand · chains A
PO4 · Phosphate ion · ion · chains A
CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	436	0.63	0.77	47	SAM, PO4, CL

Compared structures

5KQR · Structure of NS5 methyltransferase from Zika virus bound to S-adenosylmethionine · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt H9A910
Elsewhere: RCSB PDB 5KQR · PDBe 5KQR · UniProt H9A910

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