Research workbench

SETDB1 in complex with a fragment candidate

Analyse SETDB1 in complex with a fragment candidate in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5KH6
Type: protein
Length: 211 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q15047
Ligands: 6SU, SO4, CL

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	211	—	Q15047

Ligands and binding sites

6SU · methyl 3-(methylsulfonylamino)benzoate · ligand · chains A
SO4 · Sulfate ion · ion · 5 copies · chains A
CL · Chloride ion · ion · 4 copies · chains A
EDO · 1,2-ethanediol · additive · 4 copies · chains A
PEG · Di(hydroxyethyl)ether · additive · 3 copies · chains A
DMS · Dimethyl sulfoxide · additive · chains A
ACT · Acetate ion · additive · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5KH6 · SETDB1 in complex with a fragment candidate · the same entry in another collection · chain A against A, TM-score 1.00
Q15047 · AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase SETDB1 (Q15047) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q15047
Elsewhere: RCSB PDB 5KH6 · PDBe 5KH6 · UniProt Q15047

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.