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Crystal structure of CREN7-dsdna (gtaattgc) complex

Analyse Crystal structure of CREN7-dsdna (gtaattgc) complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5K07
Type: protein + DNA
Length: 73 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chromatin protein CREN7; DNA (5'-D(*GP*TP*AP*AP*TP*TP*GP*C)-3')
UniProt: Q97ZE3
Pockets: 1 · best druggability 0.37

Structure

x-ray diffraction · 2 distinct chains · 0% helix, 46% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Chromatin protein CREN7	protein	57	0% helix, 46% strand	Q97ZE3
B, C	DNA (5'-D(GPTPAPAPTPTPGPC)-3')	dna	8	—	—

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	81	0.37	0.77	12	empty

Interfaces

3 interfaces between chains.

A–B · 492 Å² buried · 8 hydrogen bonds · protein-nucleic
B–C · 366 Å² buried · 26 hydrogen bonds · nucleic-nucleic
A–C · 365 Å² buried · 2 hydrogen bonds · protein-nucleic

Compared structures

5K07 · Crystal structure of CREN7-DSDNA (GTAATTGC) complex · the same entry in another collection · chain A against A, TM-score 1.00
Q97ZE3 · AlphaFold monomer V2.0 prediction for chromatin protein CREN7 (Q97ZE3) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q97ZE3
Elsewhere: RCSB PDB 5K07 · PDBe 5K07 · UniProt Q97ZE3

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