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Bacteroides ovatus xyloglucan pul GH43A

Analyse Bacteroides ovatus xyloglucan pul GH43A in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5JOW
Type: protein
Length: 1,008 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Non-reducing end alpha-L-arabinofuranosidase BOGH43A
EC: 3.2.1.55
UniProt: A7LXT8
Pockets: 12 · best druggability 0.78

Structure

x-ray diffraction · 1 distinct chain · 5% helix, 50% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Non-reducing end alpha-L-arabinofuranosidase BOGH43A (EC 3.2.1.55)	protein	504	5% helix, 50% strand	A7LXT8

Ligands and binding sites

EDO · 1,2-ethanediol · additive · 23 copies · chains A, B
TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

12 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	857	0.78	0.81	93	TRS, EDO
2	415	0.61	0.76	46	EDO
3	374	0.61	0.77	39	empty
4	246	0.55	0.77	20	EDO
5	223	0.54	0.77	20	EDO

Interfaces

1 interface between chains.

A–B · 1329 Å² buried · 16 hydrogen bonds · protein-protein

Compared structures

5JOW · Bacteroides ovatus Xyloglucan PUL GH43A · the same entry in another collection · chain A against A, TM-score 1.00
A7LXT8 · AlphaFold monomer V2.0 prediction for non-reducing end alpha-L- arabinofuranosidase… · a predicted model of the same protein · chain B against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A7LXT8
Elsewhere: RCSB PDB 5JOW · PDBe 5JOW · UniProt A7LXT8

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