Research workbench
Crystal structure of ATG19 coiled-coil complexed with APE1 propeptide
Analyse Crystal structure of ATG19 coiled-coil complexed with APE1 propeptide in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5JGE
- Type
- protein
- Length
- 161 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Autophagy-related protein 19; APE1 propeptide
- UniProt
- P35193
- Pockets
- 1 · best druggability 0.51
Structure
x-ray diffraction · 4 distinct chains · 86% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Autophagy-related protein 19 | protein | 28 | 86% helix, 0% strand | P35193 |
| B | Autophagy-related protein 19 | protein | 27 | 93% helix, 0% strand | P35193 |
| C, F | APE1 propeptide | protein | 23 | 78% helix, 0% strand | — |
| D, E | Autophagy-related protein 19 | protein | 30 | 87% helix, 0% strand | P35193 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 164 | 0.51 | 0.78 | 20 | empty |
Interfaces
9 interfaces between chains.
- D–F · 642 Ų buried · 8 hydrogen bonds · protein-protein
- D–E · 578 Ų buried · 4 hydrogen bonds · protein-protein
- A–C · 561 Ų buried · 8 hydrogen bonds · protein-protein
- A–B · 533 Ų buried · 3 hydrogen bonds · protein-protein
- B–C · 493 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 5JGE · Crystal structure of Atg19 coiled-coil complexed with Ape1 propeptide · the same entry in another collection · chain F against F, TM-score 1.00
- P35193 · AlphaFold monomer V2.0 prediction for autophagy-related protein 19 (P35193) · a predicted model of the same protein · chain B against A, TM-score 0.80
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35193
- Elsewhere: RCSB PDB 5JGE · PDBe 5JGE · UniProt P35193
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.