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Geranylgeranyl pyrophosphate synthetase from archaeon geoglobus acetivorans

Analyse Geranylgeranyl pyrophosphate synthetase from archaeon geoglobus acetivorans in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
5JFQ
Type
protein
Length
610 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Geranylgeranyl pyrophosphate synthetase
UniProt
A0A0A7GEY4
Pockets
2 · best druggability 0.70

Structure

x-ray diffraction · 2 distinct chains · 75% helix, 1% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGeranylgeranyl pyrophosphate synthetaseprotein30476% helix, 0% strandA0A0A7GEY4
BGeranylgeranyl pyrophosphate synthetaseprotein30675% helix, 1% strandA0A0A7GEY4

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
16960.700.7756empty
26070.650.7555empty

Interfaces

1 interface between chains.

  • A–B · 1677 Ų buried · 13 hydrogen bonds · protein-protein

Compared structures

  • 5JFQ · Geranylgeranyl Pyrophosphate Synthetase from archaeon Geoglobus acetivorans · the same entry in another collection · chain A against A, TM-score 1.00

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