Research workbench
Crystal structure of the soluble domain of ania from neisseria gonorrhoeae
Analyse Crystal structure of the soluble domain of ania from neisseria gonorrhoeae in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1KBW
- Type
- protein
- Length
- 1,812 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Major outer membrane protein pan 1
- UniProt
- Q02219
- Ligands
- CU
- Pockets
- 19 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 9% helix, 45% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F | Major outer membrane protein pan 1 | protein | 302 | 9% helix, 45% strand | Q02219 |
Ligands and binding sites
- CU · Copper (II) ion · metal · 12 copies · chains A, B, C, D, E, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
19 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 491 | 0.83 | 0.89 | 79 | empty |
| 2 | 374 | 0.79 | 0.88 | 51 | empty |
| 3 | 74 | 0.75 | 0.98 | 26 | empty |
| 4 | 55 | 0.47 | 0.85 | 16 | empty |
| 5 | 56 | 0.46 | 0.84 | 16 | empty |
Interfaces
6 interfaces between chains.
- B–C · 1747 Ų buried · 25 hydrogen bonds · protein-protein
- D–E · 1742 Ų buried · 28 hydrogen bonds · protein-protein
- D–F · 1741 Ų buried · 28 hydrogen bonds · protein-protein
- A–C · 1740 Ų buried · 29 hydrogen bonds · protein-protein
- A–B · 1734 Ų buried · 24 hydrogen bonds · protein-protein
Compared structures
- 1KBW · Crystal structure of the soluble domain of ania from neisseria gonorrhoeae · the same entry in another collection · chain F against F, TM-score 1.00
- Q02219 · AlphaFold monomer V2.0 prediction for copper-containing nitrite reductase (Q02219) · a predicted model of the same protein · chain C against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q02219
- Elsewhere: RCSB PDB 1KBW · PDBe 1KBW · UniProt Q02219
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