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The structure of truncated histone-like protein

Analyse The structure of truncated histone-like protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
5ITM
Type
protein
Length
280 residues
Chains
6
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Abrb family transcriptional regulator
UniProt
A0A0E3K9N8
Pockets
1 · best druggability 0.68

Structure

x-ray diffraction · 3 distinct chains · 15% helix, 45% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B, C, DAbrb family transcriptional regulatorprotein4715% helix, 45% strandA0A0E3K9N8
EAbrb family transcriptional regulatorprotein4615% helix, 46% strandA0A0E3K9N8
FAbrb family transcriptional regulatorprotein4615% helix, 46% strandA0A0E3K9N8

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
17250.680.7676empty

Interfaces

11 interfaces between chains.

  • C–D · 1995 Ų buried · 34 hydrogen bonds · protein-protein
  • A–B · 1983 Ų buried · 32 hydrogen bonds · protein-protein
  • E–F · 1977 Ų buried · 35 hydrogen bonds · protein-protein
  • B–D · 231 Ų buried · 2 hydrogen bonds · protein-protein
  • B–F · 182 Ų buried · 4 hydrogen bonds · protein-protein

Compared structures

  • 5ITM · The structure of truncated histone-like protein · the same entry in another collection · chain A against A, TM-score 1.00

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