Research workbench
Crystal structure of the RNA recognition motif of mRNA decay regulator AUF1
Analyse Crystal structure of the RNA recognition motif of mRNA decay regulator AUF1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5IM0
- Type
- protein
- Length
- 161 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Heterogeneous nuclear ribonucleoprotein D0
- UniProt
- Q14103
- Pockets
- 1 · best druggability 0.33
Structure
x-ray diffraction · 2 distinct chains · 25% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Heterogeneous nuclear ribonucleoprotein D0 | protein | 79 | 23% helix, 42% strand | Q14103 |
| B | Heterogeneous nuclear ribonucleoprotein D0 | protein | 82 | 27% helix, 38% strand | Q14103 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 85 | 0.33 | 0.74 | 11 | empty |
Interfaces
1 interface between chains.
- A–B · 345 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 7 modified (engineered).
Compared structures
- 5IM0 · Crystal structure of the RNA recognition motif of mRNA decay regulator AUF1 · the same entry in another collection · chain A against A, TM-score 1.00
- Q14103 · AlphaFold monomer V2.0 prediction for heterogeneous nuclear ribonucleoprotein D0 (Q14103) · a predicted model of the same protein · chain B against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q14103
- Elsewhere: RCSB PDB 5IM0 · PDBe 5IM0 · UniProt Q14103
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.