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Crystal structure of a short-chain DEHYDROGENASE/REDUCTASE sdr from burkholderia vietnamiensis

Analyse Crystal structure of a short-chain DEHYDROGENASE/REDUCTASE sdr from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5IF3
Type: protein
Length: 425 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Short-chain DEHYDROGENASE/REDUCTASE sdr
UniProt: A4JKB1
Pockets: 3 · best druggability 0.56

Structure

x-ray diffraction · 2 distinct chains · 46% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Short-chain DEHYDROGENASE/REDUCTASE sdr	protein	216	46% helix, 19% strand	A4JKB1
B	Short-chain DEHYDROGENASE/REDUCTASE sdr	protein	209	47% helix, 19% strand	A4JKB1

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	212	0.56	0.79	31	empty
2	203	0.51	0.76	35	empty
3	60	0.31	0.75	19	empty

Interfaces

1 interface between chains.

A–B · 3821 Å² buried · 42 hydrogen bonds · protein-protein

Compared structures

5IF3 · Crystal structure of a Short-chain dehydrogenase/reductase SDR from Burkholderia… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A4JKB1
Elsewhere: RCSB PDB 5IF3 · PDBe 5IF3 · UniProt A4JKB1

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