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K89L mutant of glutamate dehydrogenase

Analyse K89L mutant of glutamate dehydrogenase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1K89
Type: protein
Length: 449 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glutamate dehydrogenase
EC: 1.4.1.2
UniProt: P24295
Pockets: 2 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 52% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glutamate dehydrogenase (EC 1.4.1.2)	protein	449	52% helix, 16% strand	P24295

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	685	0.74	0.80	61	empty
2	157	0.61	0.84	29	empty

Compared structures

1K89 · K89L mutant of glutamate dehydrogenase · the same entry in another collection · chain A against A, TM-score 1.00
P24295 · AlphaFold monomer V2.0 prediction for NAD-specific glutamate dehydrogenase (P24295) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P24295
Elsewhere: RCSB PDB 1K89 · PDBe 1K89 · UniProt P24295

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