Research workbench
Structure of the K. pneumonia slma protein bound to the C-terminal tail of the cytoskeletal cell division protein ftsz
Analyse Structure of the K. pneumonia slma protein bound to the C-terminal tail of the… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5HSZ
- Type
- protein
- Length
- 397 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nucleoid occlusion factor slma; C-terminal tail of ftsz
- UniProt
- A6TFN2
- Ligands
- SO4
- Pockets
- 3 · best druggability 0.59
Structure
x-ray diffraction · 3 distinct chains · 70% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nucleoid occlusion factor slma | protein | 190 | 76% helix, 0% strand | A6TFN2 |
| B | Nucleoid occlusion factor slma | protein | 196 | 69% helix, 0% strand | A6TFN2 |
| K | C-terminal tail of ftsz | protein | 11 | 0% helix, 0% strand | — |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 106 | 0.59 | 0.86 | 24 | empty |
| 2 | 88 | 0.54 | 0.85 | 23 | SO4 |
| 3 | 55 | 0.26 | 0.73 | 15 | empty |
Interfaces
2 interfaces between chains.
- A–B · 1681 Ų buried · 33 hydrogen bonds · protein-protein
- A–K · 646 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 5HSZ · Structure of the K. pneumonia SlmA protein bound to the C-terminal tail of the… · the same entry in another collection · chain A against A, TM-score 1.00
- A6TFN2 · AlphaFold monomer V2.0 prediction for nucleoid occlusion factor slma (A6TFN2) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A6TFN2
- Elsewhere: RCSB PDB 5HSZ · PDBe 5HSZ · UniProt A6TFN2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.