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Crystal structure of staphylococcus aureus sarx

Analyse Crystal structure of staphylococcus aureus sarx in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5HS5
Type: protein
Length: 232 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hth-type transcriptional regulator sarx
UniProt: Q2FIX1
Pockets: 1 · best druggability 0.29

Structure

x-ray diffraction · 1 distinct chain · 68% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Hth-type transcriptional regulator sarx	protein	116	68% helix, 9% strand	Q2FIX1

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	68	0.29	0.74	16	empty

Interfaces

1 interface between chains.

A–B · 1051 Å² buried · 4 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 modified (engineered).

Compared structures

5HS5 · Crystal structure of Staphylococcus aureus SarX · the same entry in another collection · chain A against A, TM-score 1.00
Q2FIX1 · AlphaFold monomer V2.0 prediction for hth-type transcriptional regulator sarx (Q2FIX1) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q2FIX1
Elsewhere: RCSB PDB 5HS5 · PDBe 5HS5 · UniProt Q2FIX1

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