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Oxya from actinoplanes teichomyceticus

Analyse Oxya from actinoplanes teichomyceticus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5HH3
Type: protein
Length: 774 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Oxya protein
UniProt: Q6ZZI8
Ligands: HEM
Pockets: 6 · best druggability 0.87

Structure

x-ray diffraction · 2 distinct chains · 58% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Oxya protein	protein	381	58% helix, 10% strand	Q6ZZI8
C	Oxya protein	protein	393	59% helix, 10% strand	Q6ZZI8

Ligands and binding sites

HEM · Protoporphyrin IX containing Fe · ligand · 2 copies · chains A, C
GOL · Glycerol · additive · 9 copies · chains A, C
ACT · Acetate ion · additive · 3 copies · chains A, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	970	0.87	0.88	110	HEM, GOL
2	1055	0.79	0.80	108	HEM, ACT
3	138	0.57	0.83	21	empty
4	53	0.33	0.78	13	GOL
5	77	0.29	0.72	14	empty

Interfaces

1 interface between chains.

A–C · 1624 Å² buried · 19 hydrogen bonds · protein-protein

Compared structures

5HH3 · OxyA from Actinoplanes teichomyceticus · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6ZZI8
Elsewhere: RCSB PDB 5HH3 · PDBe 5HH3 · UniProt Q6ZZI8

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