Research workbench

Crystal structure of the cyanobacterial phytochrome response regulator, rcpb

Analyse Crystal structure of the cyanobacterial phytochrome response regulator, rcpb in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1K66
Type: protein
Length: 298 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Phytochrome response regulator rcpb
UniProt: Q8RTM8
Pockets: 3 · best druggability 0.60

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Phytochrome response regulator rcpb	protein	149	42% helix, 15% strand	Q8RTM8

Ligands and binding sites

BME · Beta-mercaptoethanol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	60	0.60	0.91	16	empty
2	65	0.58	0.89	18	empty
3	72	0.40	0.79	23	empty

Interfaces

1 interface between chains.

A–B · 1313 Å² buried · 18 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 covalent (additive adduct).

Compared structures

1K66 · Crystal Structure of the Cyanobacterial Phytochrome Response Regulator, RcpB · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8RTM8
Elsewhere: RCSB PDB 1K66 · PDBe 1K66 · UniProt Q8RTM8

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.