Research workbench
Bacterial initiation protein in complex with phage inhibitor protein
Analyse Bacterial initiation protein in complex with phage inhibitor protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5HE9
- Type
- protein
- Length
- 224 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Helicase loader; Phage inhibitor protein
- UniProt
- W8TSU2, A0A0J7LG86
- Ligands
- ADP, BEF, MG
- Pockets
- 1 · best druggability 0.37
Structure
x-ray diffraction · 2 distinct chains · 60% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Helicase loader | protein | 168 | 56% helix, 14% strand | W8TSU2 |
| E | Phage inhibitor protein | protein | 56 | 71% helix, 5% strand | A0A0J7LG86 |
Ligands and binding sites
- ADP · Adenosine-5'-diphosphate · ligand · chains A
- BEF · Beryllium trifluoride ion · ligand · chains A, E
- MG · Magnesium ion · metal · chains A, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 64 | 0.37 | 0.79 | 17 | BEF, MG |
Interfaces
1 interface between chains.
- A–E · 1240 Ų buried · 13 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 5HE9 · Bacterial initiation protein in complex with Phage inhibitor protein · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt W8TSU2
- Every structure of UniProt A0A0J7LG86
- Elsewhere: RCSB PDB 5HE9 · PDBe 5HE9 · UniProt W8TSU2 · UniProt A0A0J7LG86
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