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Crystal structure of chaetomium thermophilum NIC96 sol

Analyse Crystal structure of chaetomium thermophilum NIC96 sol in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5HB2
Type: protein
Length: 716 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nucleoporin NIC96
UniProt: G0S024
Pockets: 11 · best druggability 0.65

Structure

x-ray diffraction · 1 distinct chain · 61% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
C	Nucleoporin NIC96	protein	716	61% helix, 2% strand	G0S024

Pockets

11 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	359	0.65	0.80	45	empty
2	157	0.52	0.80	21	empty
3	146	0.48	0.78	24	empty
4	103	0.46	0.79	16	empty
5	105	0.43	0.78	18	empty

Modifications

Observed in the structure: 23 modified (engineered).

Compared structures

5HB2 · Crystal Structure of Chaetomium thermophilum Nic96 SOL · the same entry in another collection · chain C against C, TM-score 1.00
G0S024 · AlphaFold monomer V2.0 prediction for nucleoporin NIC96 (G0S024) · a predicted model of the same protein · chain C against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G0S024
Elsewhere: RCSB PDB 5HB2 · PDBe 5HB2 · UniProt G0S024

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