Research workbench
The crystal structure of nucleoplasmin-core
Analyse The crystal structure of nucleoplasmin-core in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1K5J
- Type
- protein
- Length
- 462 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nucleoplasmin core
- UniProt
- P05221
- Pockets
- 3 · best druggability 0.86
Structure
x-ray diffraction · 5 distinct chains · 0% helix, 61% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nucleoplasmin core | protein | 94 | 0% helix, 60% strand | P05221 |
| B | Nucleoplasmin core | protein | 96 | 0% helix, 64% strand | P05221 |
| C | Nucleoplasmin core | protein | 89 | 0% helix, 60% strand | P05221 |
| D | Nucleoplasmin core | protein | 90 | 0% helix, 61% strand | P05221 |
| E | Nucleoplasmin core | protein | 93 | 0% helix, 62% strand | P05221 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 426 | 0.86 | 0.93 | 38 | empty |
| 2 | 50 | 0.48 | 0.86 | 18 | empty |
| 3 | 60 | 0.28 | 0.74 | 13 | empty |
Interfaces
5 interfaces between chains.
- A–B · 883 Ų buried · 9 hydrogen bonds · protein-protein
- A–E · 877 Ų buried · 8 hydrogen bonds · protein-protein
- B–C · 870 Ų buried · 7 hydrogen bonds · protein-protein
- C–D · 838 Ų buried · 7 hydrogen bonds · protein-protein
- D–E · 836 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P05221
- Elsewhere: RCSB PDB 1K5J · PDBe 1K5J · UniProt P05221
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.