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Crystal structure of an asymmetric dimer of the geobacillus stearothermophilus smc hinge domain

Analyse Crystal structure of an asymmetric dimer of the geobacillus stearothermophilus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5H69
Type: protein
Length: 497 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chromosome partition protein smc
UniProt: A0A0K2H586
Pockets: 3 · best druggability 0.44

Structure

x-ray diffraction · 2 distinct chains · 60% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Chromosome partition protein smc	protein	252	61% helix, 13% strand	A0A0K2H586
B	Chromosome partition protein smc	protein	245	60% helix, 14% strand	A0A0K2H586

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	55	0.44	0.83	13	empty
2	102	0.35	0.73	21	empty
3	70	0.30	0.73	22	empty

Interfaces

1 interface between chains.

A–B · 1233 Å² buried · 26 hydrogen bonds · protein-protein

Compared structures

5H69 · Crystal structure of an asymmetric dimer of the Geobacillus stearothermophilus SMC hinge… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0K2H586
Elsewhere: RCSB PDB 5H69 · PDBe 5H69 · UniProt A0A0K2H586

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