Research workbench
Crystal structure of CBLN4
Analyse Crystal structure of CBLN4 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5H4C
- Type
- protein
- Length
- 401 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein CBLN4
- UniProt
- D4ABJ2
- Ligands
- NAG
- Pockets
- 3 · best druggability 0.83
Structure
x-ray diffraction · 3 distinct chains · 2% helix, 53% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein CBLN4 | protein | 134 | 4% helix, 51% strand | D4ABJ2 |
| B | Protein CBLN4 | protein | 135 | 3% helix, 54% strand | D4ABJ2 |
| C | Protein CBLN4 | protein | 132 | 0% helix, 54% strand | D4ABJ2 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 204 | 0.83 | 0.97 | 42 | empty |
| 2 | 184 | 0.76 | 0.92 | 41 | empty |
| 3 | 174 | 0.52 | 0.78 | 21 | empty |
Interfaces
3 interfaces between chains.
- A–C · 851 Ų buried · 4 hydrogen bonds · protein-protein
- A–B · 843 Ų buried · 5 hydrogen bonds · protein-protein
- B–C · 842 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 glycan (N-glycosylation).
Compared structures
- 5H4C · Crystal structure of Cbln4 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D4ABJ2
- Elsewhere: RCSB PDB 5H4C · PDBe 5H4C · UniProt D4ABJ2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.