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Crystal structures of the tric trimeric intracellular cation channel orthologue from rhodobacter sphaeroides
Analyse Crystal structures of the tric trimeric intracellular cation channel orthologue… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5H36
- Type
- protein
- Length
- 387 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein tric
- UniProt
- Q3HKN0
- Ligands
- PX4
- Pockets
- 3 · best druggability 0.71
Structure
x-ray diffraction · 2 distinct chains · 80% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| E | Uncharacterized protein tric | protein | 194 | 80% helix, 0% strand | Q3HKN0 |
| A | Uncharacterized protein tric | protein | 193 | 80% helix, 0% strand | Q3HKN0 |
Ligands and binding sites
- PX4 · 1,2-dimyristoyl-sn-glycero-3-phosphocholine · ligand · 2 copies · chains E, A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 660 | 0.71 | 0.78 | 61 | empty |
| 2 | 92 | 0.44 | 0.79 | 23 | empty |
| 3 | 54 | 0.34 | 0.78 | 17 | empty |
Interfaces
1 interface between chains.
- E–A · 305 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 5H36 · Crystal structures of the TRIC trimeric intracellular cation channel orthologue from… · the same entry in another collection · chain E against E, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q3HKN0
- Elsewhere: RCSB PDB 5H36 · PDBe 5H36 · UniProt Q3HKN0
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