Research workbench

Crystal structure of WD40 repeat domains of GEMIN5

Analyse Crystal structure of WD40 repeat domains of GEMIN5 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5H1J
Type: protein
Length: 693 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Gem-associated protein 5
UniProt: Q8TEQ6
Pockets: 8 · best druggability 0.80

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 45% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Gem-associated protein 5	protein	693	6% helix, 45% strand	Q8TEQ6

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	974	0.80	0.82	66	empty
2	479	0.74	0.83	47	empty
3	400	0.62	0.77	43	empty
4	151	0.45	0.76	28	empty
5	69	0.41	0.80	23	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

5H1J · Crystal structure of WD40 repeat domains of Gemin5 · the same entry in another collection · chain A against A, TM-score 1.00
Q8TEQ6 · AlphaFold monomer V2.0 prediction for gem-associated protein 5 (Q8TEQ6) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8TEQ6
Elsewhere: RCSB PDB 5H1J · PDBe 5H1J · UniProt Q8TEQ6

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.