Research workbench
Crystal structure of deep vent DNA polymerase
Analyse Crystal structure of deep vent DNA polymerase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5H12
- Type
- protein
- Length
- 753 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Deep vent DNA polymerase
- Pockets
- 5 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Deep vent DNA polymerase | protein | 753 | 41% helix, 21% strand | — |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 383 | 0.62 | 0.77 | 41 | empty |
| 2 | 310 | 0.60 | 0.78 | 42 | empty |
| 3 | 201 | 0.51 | 0.76 | 20 | empty |
| 4 | 93 | 0.45 | 0.80 | 15 | empty |
| 5 | 81 | 0.30 | 0.72 | 23 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 5H12 · Crystal structure of Deep Vent DNA Polymerase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 5H12 · PDBe 5H12
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