Research workbench
Kinesin-8 motor, KIF19A, in the nucleotide-free state complexed with GDP-taxol microtubule
Analyse Kinesin-8 motor, KIF19A, in the nucleotide-free state complexed with GDP-taxol… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5GSY
- Type
- protein
- Length
- 329 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Kinesin-like protein KIF19
- UniProt
- Q99PT9
- Pockets
- 3 · best druggability 0.44
Structure
electron microscopy · 1 distinct chain · 29% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| K | Kinesin-like protein KIF19 | protein | 329 | 29% helix, 26% strand | Q99PT9 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 127 | 0.44 | 0.77 | 17 | empty |
| 2 | 70 | 0.41 | 0.79 | 17 | empty |
| 3 | 91 | 0.33 | 0.74 | 19 | empty |
Compared structures
- 5GSY · Kinesin-8 motor, KIF19A, in the nucleotide-free state complexed with GDP-taxol microtubule · the same entry in another collection · chain K against K, TM-score 1.00
- Q99PT9 · AlphaFold monomer V2.0 prediction for kinesin-like protein KIF19 (Q99PT9) · a predicted model of the same protein · chain K against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99PT9
- Elsewhere: RCSB PDB 5GSY · PDBe 5GSY · UniProt Q99PT9
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