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Crystal structure of tla-3 extended-spectrum beta-lactamase

Analyse Crystal structure of tla-3 extended-spectrum beta-lactamase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5GS8
Type: protein
Length: 275 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beta-lactamase
EC: 3.5.2.6
UniProt: A0A0B6VPP7
Ligands: NA, SO4, CL
Pockets: 1 · best druggability 0.44

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-lactamase (EC 3.5.2.6)	protein	275	46% helix, 20% strand	A0A0B6VPP7

Ligands and binding sites

NA · Sodium ion · metal · 15 copies · chains A
SO4 · Sulfate ion · ion · 5 copies · chains A
CL · Chloride ion · ion · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	144	0.44	0.76	22	SO4

Compared structures

5GS8 · Crystal structure of TLA-3 extended-spectrum beta-lactamase · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0B6VPP7
Elsewhere: RCSB PDB 5GS8 · PDBe 5GS8 · UniProt A0A0B6VPP7

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