Research workbench
The sensor domain structure of the zinc-responsive histidine kinase czcs from pseudomonas aeruginosa
Analyse The sensor domain structure of the zinc-responsive histidine kinase czcs from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5GPO
- Type
- protein
- Length
- 245 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sensor protein czcs
- EC
- 2.7.13.3
- UniProt
- A0A0C7CWG4
- Ligands
- ZN, SO4
- Pockets
- 2 · best druggability 0.53
Structure
x-ray diffraction · 2 distinct chains · 40% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sensor protein czcs (EC 2.7.13.3) | protein | 121 | 41% helix, 31% strand | A0A0C7CWG4 |
| B | Sensor protein czcs (EC 2.7.13.3) | protein | 124 | 39% helix, 31% strand | A0A0C7CWG4 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 257 | 0.53 | 0.76 | 28 | empty |
| 2 | 50 | 0.25 | 0.73 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 2445 Ų buried · 21 hydrogen bonds · protein-protein
Compared structures
- 5GPO · The sensor domain structure of the zinc-responsive histidine kinase CzcS from Pseudomonas… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0C7CWG4
- Elsewhere: RCSB PDB 5GPO · PDBe 5GPO · UniProt A0A0C7CWG4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.