Research workbench
Myotubularin-related protein 2
Analyse Myotubularin-related protein 2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5GNH
- Type
- protein
- Length
- 1,012 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Myotubularin-related protein 2
- EC
- 3.1.3.95, 3.1.3.64
- UniProt
- Q13614
- Ligands
- PO4
- Pockets
- 12 · best druggability 0.68
Structure
x-ray diffraction · 2 distinct chains · 39% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Myotubularin-related protein 2 (EC 3.1.3.95, 3.1.3.64) | protein | 506 | 39% helix, 17% strand | Q13614 |
| B | Myotubularin-related protein 2 (EC 3.1.3.95, 3.1.3.64) | protein | 506 | 39% helix, 17% strand | Q13614 |
Ligands and binding sites
- PO4 · Phosphate ion · ion · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
12 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 280 | 0.68 | 0.83 | 29 | empty |
| 2 | 256 | 0.68 | 0.84 | 27 | empty |
| 3 | 431 | 0.67 | 0.79 | 38 | empty |
| 4 | 251 | 0.55 | 0.77 | 32 | empty |
| 5 | 152 | 0.51 | 0.79 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 956 Ų buried · 18 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13614
- Elsewhere: RCSB PDB 5GNH · PDBe 5GNH · UniProt Q13614
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