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Crystal structure of N19D potato sti-kunitz bi-functional inhibitor of serine and aspartic proteases in space group C2221 and pH 3.5
Analyse Crystal structure of N19D potato sti-kunitz bi-functional inhibitor of serine… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5FZY
- Type
- protein
- Length
- 370 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Kti-a protein
- UniProt
- A0A097H118
- Pockets
- 3 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 7% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Kti-a protein | protein | 185 | 7% helix, 36% strand | A0A097H118 |
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 191 | 0.65 | 0.84 | 28 | empty |
| 2 | 231 | 0.51 | 0.76 | 34 | empty |
| 3 | 57 | 0.51 | 0.87 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 595 Ų buried · 9 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
- 5FZY · Crystal structure of N19D potato sti-kunitz bi-functional inhibitor of serine and… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A097H118
- Elsewhere: RCSB PDB 5FZY · PDBe 5FZY · UniProt A0A097H118
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