Research workbench

Last common ancestor of gram-negative bacteria (GNCA4) beta-lactamase class a

Analyse Last common ancestor of gram-negative bacteria (GNCA4) beta-lactamase class a in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5FQQ
Type: protein
Length: 262 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: GNCA4 lactamase
EC: 3.5.2.6
Pockets: 1 · best druggability 0.27

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	GNCA4 lactamase (EC 3.5.2.6)	protein	262	46% helix, 18% strand	—

Ligands and binding sites

PG0 · 2-(2-methoxyethoxy)ethanol · additive · chains A
PEG · Di(hydroxyethyl)ether · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	58	0.27	0.74	17	empty

Compared structures

5FQQ · Last common ancestor of Gram-negative bacteria (GNCA4) beta-lactamase class A · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 5FQQ · PDBe 5FQQ

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