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Crystal structure of the focal adhesion targeting domain of focal adhesion kinase

Analyse Crystal structure of the focal adhesion targeting domain of focal adhesion… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1K04
Type: protein
Length: 142 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Focal adhesion kinase 1
EC: 2.7.1.112
UniProt: Q05397
Ligands: CL
Pockets: 1 · best druggability 0.34

Structure

x-ray diffraction · 1 distinct chain · 78% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Focal adhesion kinase 1 (EC 2.7.1.112)	protein	142	78% helix, 0% strand	Q05397

Ligands and binding sites

CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	58	0.34	0.76	11	empty

Compared structures

1K04 · Crystal Structure of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase · the same entry in another collection · chain A against A, TM-score 1.00
Q05397 · AlphaFold monomer V2.0 prediction for focal adhesion kinase 1 (Q05397) · a predicted model of the same protein · chain A against A, TM-score 0.73

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q05397
Elsewhere: RCSB PDB 1K04 · PDBe 1K04 · UniProt Q05397

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