Research workbench
Crystal structure of ctspd
Analyse Crystal structure of ctspd in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5FBY
- Type
- protein
- Length
- 501 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Separase; Cleaved peptide
- UniProt
- G0SHM3
- Pockets
- 6 · best druggability 0.52
Structure
x-ray diffraction · 2 distinct chains · 47% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Separase | protein | 490 | 47% helix, 14% strand | G0SHM3 |
| B | Cleaved peptide | protein | 11 | 36% helix, 0% strand | — |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 189 | 0.52 | 0.78 | 31 | empty |
| 2 | 155 | 0.50 | 0.78 | 21 | empty |
| 3 | 62 | 0.37 | 0.78 | 15 | empty |
| 4 | 101 | 0.36 | 0.74 | 22 | empty |
| 5 | 54 | 0.32 | 0.77 | 21 | empty |
Interfaces
1 interface between chains.
- A–B · 701 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 5FBY · Crystal structure of ctSPD · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G0SHM3
- Elsewhere: RCSB PDB 5FBY · PDBe 5FBY · UniProt G0SHM3
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