Research workbench
Crystal structure of the PRP38-MFAP1 complex of chaetomium thermophilum
Analyse Crystal structure of the PRP38-MFAP1 complex of chaetomium thermophilum in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5F5T
- Type
- protein
- Length
- 537 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative uncharacterized protein
- UniProt
- G0S1D3, G0SHD7
- Pockets
- 3 · best druggability 0.79
Structure
x-ray diffraction · 4 distinct chains · 62% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative uncharacterized protein | protein | 215 | 57% helix, 9% strand | G0S1D3 |
| B | Putative uncharacterized protein | protein | 214 | 58% helix, 9% strand | G0S1D3 |
| C | Putative uncharacterized protein | protein | 64 | 81% helix, 0% strand | G0SHD7 |
| D | Putative uncharacterized protein | protein | 44 | 80% helix, 0% strand | G0SHD7 |
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1098 | 0.79 | 0.81 | 89 | empty |
| 2 | 250 | 0.59 | 0.79 | 34 | empty |
| 3 | 223 | 0.59 | 0.80 | 34 | empty |
Interfaces
6 interfaces between chains.
- A–C · 1140 Ų buried · 20 hydrogen bonds · protein-protein
- B–D · 1129 Ų buried · 26 hydrogen bonds · protein-protein
- C–D · 446 Ų buried · 2 hydrogen bonds · protein-protein
- A–B · 381 Ų buried · 4 hydrogen bonds · protein-protein
- B–C · 224 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 5F5T · Crystal structure of the Prp38-MFAP1 complex of Chaetomium thermophilum · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G0S1D3
- Every structure of UniProt G0SHD7
- Elsewhere: RCSB PDB 5F5T · PDBe 5F5T · UniProt G0S1D3 · UniProt G0SHD7
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