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Crystal structure of marburg virus nucleoprotein core domain
Analyse Crystal structure of marburg virus nucleoprotein core domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5F5M
- Type
- protein
- Length
- 675 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nucleoprotein
- UniProt
- Q6UY69
- Pockets
- 8 · best druggability 0.57
Structure
x-ray diffraction · 2 distinct chains · 66% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nucleoprotein | protein | 341 | 65% helix, 6% strand | Q6UY69 |
| B | Nucleoprotein | protein | 334 | 66% helix, 4% strand | Q6UY69 |
Pockets
8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 260 | 0.57 | 0.78 | 38 | empty |
| 2 | 244 | 0.53 | 0.76 | 41 | empty |
| 3 | 71 | 0.38 | 0.78 | 13 | empty |
| 4 | 98 | 0.37 | 0.75 | 16 | empty |
| 5 | 77 | 0.36 | 0.77 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 1443 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 5F5M · Crystal structure of Marburg virus nucleoprotein core domain · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6UY69
- Elsewhere: RCSB PDB 5F5M · PDBe 5F5M · UniProt Q6UY69
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